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Panorama – Expecting Parents

Completely safe prenatal screening, with no risk and unlike the more common pregnancy test procedures, this NIPT test is highly accurate and totally non-invasive.

WHAT IS PANORAMA?

PANORAMA IS A NON-INVASIVE PRENATAL SCREENING TEST (NIPT) performed through a simple blood draw from your arm. During pregnancy, some of the DNA from the baby crosses into the mother’s bloodstream. Panorama looks at this DNA to see if there is evidence of certain genetic conditions that could affect the baby’s health.

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BOOK YOUR PANORAMA TEST (NIPT) APPOINTMENT

Book your PANORAMA Non Invasive Prenatal Screening Test (NIPT) now at Scientific Clinical Laboratories

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IS PANORAMA RIGHT FOR ME?

Some women have a higher chance of their baby being affected with certain conditions like Down syndrome, especially if they:

  • Are over the age of 35
  • Have certain family histories
  • Have abnormal ultrasound findings
  • Have abnormal blood test results

 

Panorama is designed for all pregnant women regardless of age with the exception of women with the following types of pregnancies:

  • Multiple gestation pregnancies
  • Pregnancies that are using an egg donor or a surrogate
  • Pregnant women who are bone marrow transplant Recipients

WHAT DOES PANORAMA TELL ME?

Panorama screens for common genetic conditions that are caused by extra or missing chromosomes in the baby’s DNA:

  • Down Syndrome (Trisomy 21)
  • Edwards Syndrome (Trisomy 18)
  • Patau Syndrome (Trisomy 13)
  • Triploidy
  • Vanishing Twin
  • Sex Chromosome Abnormalities:
  • Turner Syndrome (Monosomy X)
  • Klinefelter Syndrome (XXY)
  • Jacobs Syndrome (XYY)
  • Triple X Syndrome (XXX)
In addition to the above chromosomal abnormalities, you can optionally screen for five microdeletion syndromes associated with serious health problems:

 

  • 22q11.2 Deletion (DiGeorge) Syndrome
  • 1p36 Deletion Syndrome
  • Angelman Syndrome
  • Prader-Willi Syndrome
  • Cri-du-chat

 

What are MICRODELETIONS?

A microdeletion is a when a small piece of a chromosome is missing.  Some microdeletions are known to cause specific genetic syndromes.  Unlike Down syndrome and many other conditions, the chance of having a child with a microdeletion is the same regardless of the age of the mother.  So, a 28 year old has the same chance as a 38 year old – and a greater risk of having a child with a microdeletion than Down syndrome.  The most common microdeletion syndrome is 22q11.2 deletion syndrome, also known as 22q or DiGeorge syndrome, which occurs in 1 in 2000 live births.  Prenatal screening for microdeletions is particularly important because they can be difficult to diagnose in infants, and early childhood intervention can have a significant positive impact on the long term health of the baby.

To learn more about all the above these conditions, click here (this is a link to the Conditions pdf)

Panorama can also tell you the baby’s gender, if you so choose.

How Panorama works & Important Details

How does Panorama work and why is it DIFFERENT?

Panorama™ is the ONLY non-invasive prenatal screening test that distinguishes between fetal and maternal cell-free DNA thanks to SNP-based sequencing and Natera’s proprietary Natus™ (Next-Generation Aneuploidy Test Using SNPs) algorithm.

To know more about how the technology works, please click here

capture2Important Test Details:

  • EARLY: Can be done as early as 9 weeks into your pregnancy.
  • SAFE: Brings no risk to your baby. Requires only a blood draw from your arm.
  • FAST: Results within 10-12 days
  • ACCURATE: >99% sensitivity and specificity
  • GENDER: know the sex of your baby at 9 weeks!

This is how your result report will look like:

UNDERSTANDING MY PANORAMA TEST RESULTS

What if I receive a HIGH RISK result?

Panorama gives you a personalized risk score and tells you if the baby is at high risk or low risk for the conditions it screens for. Like other prenatal screening tests, Panorama does not provide a definitive diagnosis of the condition. If you have a high-risk result your doctor will recommend a diagnostic test, typically CVS or amniocentesis.

 

  • Chorionic villus sampling (CVS) is done between 10 and 12 weeks in pregnancy. A small sample of the developing placenta is taken by passing a thin needle through the lower abdomen or using a flexible plastic tube through the vagina.
  • Amniocentesis (amnio) is usually done between 15 and 22 weeks in pregnancy. A small amount of the fluid that surrounds the baby is taken by passing a thin needle through the abdomen.
  • If you choose not to undergo invasive testing, confirmatory testing can be performed on the baby after delivery.

Both CVS and amniocentesis accurately diagnose chromosome problems by examining fetal cells under a microscope. However, both of these tests havea small risk for miscarriage.

All screening tests may provide “high-risk” results when your baby is completely healthy (false positive) or may miss a chromosomal disorder (false negative). Maternal serum screening tests, also known as first-trimester screen, quad screen or integrated screen, miss one out of seven affected pregnancies and identify twenty “high-risk” moms for every one mom who is actually carrying an affected baby.

Panorama™ is significantly more accurate. Women who have a “low-risk” result have less than 1 in 10,000 chance of carrying an affected child and 9 out of 10 “high risk” results are accurate. It is important to emphasize that all women with a “high risk” result should receive genetic counseling and be offered a diagnostic procedure for confirmation of these screening results.

Note: Even though the Panaroma is highly accurate compared to the conventional methods, this is still considered as a screening test.

  • What if I do not get a result?

Please click here to understand why sometimes the test is unable to provide a result.